President Rouhani said the US administration is no more able to prove its trustworthiness for any negotiations after its withdrawal from the Iran nuclear deal and a number of other international treaties.
"We are always in favor of diplomacy and talks ... But talks need honesty ... The US re-imposes sanctions on Iran and pulls out of the nuclear deal, and then wants to hold talks with us," the Iranian president said.
He added that the US must first prove itself willing to solve problems through negotiations after its withdrawal from the JCPOA.
"Negotiations with sanctions don't make sense. They are imposing sanctions on Iranian children, patients and the nation," Iran's chief executive said.
"If you're an enemy and you stab the other person with a knife and then you say you want negotiations, then the first thing you have to do is remove the knife," he added.
The Iranian president further stated that a recent call by US President Donald Trump for direct talks with Iran was only aimed at creating division in the country.
"Trump's call for direct talks is only for domestic consumption in America ... and to create division in Iran," Rouhani pointed out.
"They want to launch psychological warfare against the Iranian nation," he added.
During the televised interview, Rouhani said by withdrawing from the JCPOA, Trump aimed to make Iran leave the nuclear accord as well to lose all it had achieved through the deal.
He said Trump did not want its anti-Iran sanctions to be unilateral and wanted the entire world to impose sanctions on Iran, but he failed to achieve this goal.
“Even today, which sanctions have been re-imposed [by the United States], Europe has stood against America. This is while Europe was always an ally of America,” the Iranian president said.
Noting that the United States will regret imposing sanctions on Iran, Rouhani emphasized that the Iranian nation can overcome all economic hardships through unity.